NON-STEROID ANTI-INFLAMMATORY DRUGS: GASTROINTESTINAL COMPLICATIONS IN TREATMENT
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Analysis of the treatment results in 275 patients with acute gastrointestinal bleeding from the urgent surgical department of Bukhara branch of the Republican cientific Center for Emergency Medical Care##common.commaListSeparator## upper gastrointestinal tract, bleeding, endoscopic hemostasis, surgical treatment, conservative therapy.Abstrak
To date, the world medical literature presents a huge amount of data on the side effects of NSAID therapy, primarily on their toxic effects on the gastrointestinal tract (GIT). It is known that NSAID-induced erosive and ulcerative damage can be localized in almost any part of the digestive tract. However, traditionally the subject of discussion is NSAID-induced damage to the mucous membrane of the gastroduodenal zone . Nevertheless, the toxic effects of NSAIDs on the small intestine (NSAID-induced enteropathy), despite the relatively rare discussion in the literature, is much more common than is commonly believed.
Endoscopic methods of hemostasis in bleeding from the upper gastrointestinal tract (argon plasma coagulation, combined prolonged infiltration hemostasis with the use of 6% solution of polyglucin with mafusol, irrigation with the solution ligation of the esophageal veins and Danis stent implantation) were applied to 275 patients. All patients simultaneously received conservative treatment. When using the methods of endoscopic hemostasis mentioned above in patients with bleeding from upper gastrointestinal tract the efficiency was achieved in 87.9% of cases. It was the highest when using combined endoscopic methods. Recurrent acute bleeding was diagnosed in 30 (7.1%) cases.
Conclusion. The efficacy of endoscopic methods of hemostasis in bleeding
