COVID-АССОЦИИРОВАННАЯ КОАГУЛОПАТИЯ У ПАЦИЕНТОВ НОВОЙ КОРОНАВИРУСНОЙ ИНФЕКЦИИ
Keywords:
Ключевые слова: COVID-19, коагуляция, протромбиновое время, продукты распада фибрина, D-димер, антифосфолипидные антитела, прогноз.Abstract
Изучено значение показателей коагуляции D-димера (DD), протромбинового времени (ПВ), активированного частичного тромбопластинового времени (AЧTВ), тромбинового времени (TВ) и фибриногена (Фг) в прогнозировании тяжести и прогноза COVID-19. Нарушение функции свертывания крови встречался почти у всех, чаще у тяжелых пациентов. Показатели гемостатического гомеостаза, как D-димер, протромбиновое время и фибриноген могут быть использованы в качестве предикторами тяжести течения болезни у пациентов.
References
1. World Health Organization. Novel Coronavirus ( 2019-nCoV) situation reports. https://www.worldometers.info/coronavirus/ Accessed: 28 Sept. 2021.
2. Oblokulov AR , Musaeva DM, Elmuradova AA (2020 ) Clinical and epidemiological characteristics of the new coronavirus infection (COVID-19). // New Day in Medicine. No2 (30/2) p.110-115.
3. Bikdeli B , Madhavan MV, Jimenez D et al. COVID- 19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up. JACC. 2020. doi:10.1016/j.jacc.2020.04.031 .
4. Husenova Z. Z, & Oblokulov A. R. (2021). Clinical and epidemiological characteristics of patients with severe form of COVID-19. CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, 2(3), 282-285. https://doi.org/10.47494/cajmns.v2i3.213.
5. Cao Y. , Liu X., Xiong L. et al. Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2: a systematic review and meta-analysis. J. Med. Virol ., 2020 ; doi : 10.1002/jmv.25 822
6. Melhem A., Stem M., Shibolet O. et al, Treatment of chronic hepatitis С virus infection via antioxidants. Results of a phase clinical trial. J. CIin. Gastroenterol. 2005; 39: 737-742.
7. Okanue L, Sakamoto S., Iton Y. et al. Побочные эффекты лечения хронического гепатита С высокими дозами интер¬ферона. J. Hepatol. 1996; 25: 283-291.
8. Ibrokhimovna, M. M. . (2024). Improvement of Primary Prophylaxis and Treatment of Spontaneous Bacterial Peritonitis Complicated in Virus Etiology Liver Cirrhosis. Journal of Intellectual Property and Human Rights, 3(4), 19–25. Retrieved from http://journals.academiczone.net/index.php/jiphr/article/view/2506
9. Elmurodova A.A. (2023). Viral Hepatitis Delta: An Underestimated Threat. Texas Journal of Medical Science, 26, 1–3. Retrieved from https://zienjournals.com/index.php/tjms/article/view/4610
10. Oblokulov Abdurashid Rakhimovich Mukhammadieva Musharraf Ibrokhimovna Sanokulova Sitora Avazovna Khadieva Dora Isakovna. (2023). CLINICAL AND LABORATORY FEATURES OF SPONTANEOUS BACTERIAL PERITONITIS IN PATIENTS WITH VIRAL LIVER CIRRHOSIS. Journal of Advanced Zoology, 44(S2), 3744–3750. Retrieved from http://www.jazindia.com/index.php/jaz/article/view/1716
11. Mukhammadieva M.I. (2022). Modern clinical and biochemical characteristics of liver cirrhosis patients of viral etiology with spontaneous bacterial peritonitis //Texas Journal of Medical Science. – 2022.- P. 86-90
12. Abdulloev Mukhriddin Ziyodulloevich. (2023). Modern Therapy of Viral Hepatitis. Texas Journal of Medical Science, 26, 66–69. Retrieved from https://www.zienjournals.com/index.php/tjms/article/view/4636
13. Nabiyeva, Z. . (2023). CLINICAL MANIFESTATIONS OF CHRONIC DISEASES ОРГАНОВ OF THE DIGESTIVE SYSTEM IN CHILDREN. Инновационные исследования в современном мире: теория и практика, 2(15), 27–28. извлечено от https://in-academy.uz/index.php/zdit/article/view/13239
14. Mukhammadieva M.I. (2023). Вирус этиологияли жигар циррози беморларида спонтан бактериал перитонит билан асоратланишнинг профилактикаси ва давосини такомиллаштириш//Oriental Renaissance: Innovative, educational, natural and social sciences. -2023.-P.947-953.
15. Oblokulov A.R., M.I.Mukhammadieva.(2022). Clinical and biochemical characteristics of liver cirrhosis patients of viral etiology with spontaneous bacterial peritonitis//Academicia Globe: Indersciense Research.-2022.- P. 210-216.
16. Khadieva Dora Isakovna. (2024). Diagnosis and Prediction of Liver Fibrosis in Chronic Viral Hepatitis C in Hiv-Infected. International Journal of Integrative and Modern Medicine, 2(6), 89–94. Retrieved from https://medicaljournals.eu/index.php/IJIMM/article/view/515
17. Кароматов Иномжон Джураевич, Набиева Зумрад Тухтаевна Адаптоген - элеутерококк, свободоягодник колючий (обзор литературы) // Биология и интегративная медицина. 2017. №11. URL: https://cyberleninka.ru/article/n/adaptogen-eleuterokokk-svobodoyagodnik-kolyuchiy-obzor-literatury (дата обращения: 19.12.2023).
18. Mukhammadieva Musharraf Ibrokhimovna. (2024). TREATMENT OF SPONTANEOUS BACTERIAL PERITONITIS COMPLICATED IN VIRUS ETIOLOGY LIVER CIRRHOSIS. JOURNAL OF EDUCATION, ETHICS AND VALUE, 3(6), 73–80. Retrieved from https://jeev.innovascience.uz/index.php/jeev/article/view/723
19. Sanokulova Sitora Avazovna. (2023). Factors of Development of Hepatorenal Syndrome in Patients with Liver Cirrhosis of Viral Etiology. Texas Journal of Medical Science, 26, 4–9. Retrieved from https://www.zienjournals.com/index.php/tjms/article/view/4611
20. Tukhtaboevna, M. Z. . (2022). ACUTE INTESTINAL INFECTIONS IN CHILDREN, MODERN PRINCIPLES OF CORRECTION AND RESTORATION OF WATER-ELECTROLYTE BALANCE. IJTIMOIY FANLARDA INNOVASIYA ONLAYN ILMIY JURNALI, 101–105. Retrieved from https://sciencebox.uz/index.php/jis/article/view/3249
21. Tukhtaboevna M. Z. Choosing an Antihistamine to Treat Seasonal Allergies //INTERNATIONAL JOURNAL OF HEALTH SYSTEMS AND MEDICAL SCIENCES. – 2022. – Т. 1. – №. 4. – С. 401-407.
22. Jalilova, А.S. (2022). THE SPREAD OF CIRRHOSIS OF THE LIVER BY ETIOLOGICAL FACTORS. Oriental renaissance: Innovative, educational, natural and social sciences, 2 (6), 253-257.
23. A. A., E., A. S., D., & A., M. S. (2022). Modern Approaches to Treatment of Chronic Giardiasis. Central Asian Journal of Medical and Natural Science, 3(2), 102-105. Retrieved from https://www.cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/631
24. Облоқулов, А., & Муҳаммадиева, М. (2022). КЛИНИКО-ЛАБОРАТОРНАЯ ХАРАКТЕРИСТИКА СПОНТАННОГО БАКТЕРИАЛЬНОГО ПЕРИТОНИТА ПРИ ЦИРРОЗЕ ПЕЧЕНИ ВИРУСНОЙ ЭТИОЛОГИИИ. Журнал вестник врача, 1(3), 66–69. извлечено от https://inlibrary.uz/index.php/doctors_herald/article/view/2016
25. Oblokulova Z.I, Oblokulov A.R, & Jalilova A.S. (2022). Diagnostic Significance of Hepatic Fibrosis in Patients with Extrahepatic Chronic Viral Hepatitis C. Central Asian Journal of Medical and Natural Science, 3(3), 438-443. Retrieved from https://www.cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/806
26. Aslonova.M.R. (2022). Determination of suicidality against the background of Parasitic Diseases in children // INTERNATIONAL JOURNAL OF PHILOSOPHICAL STUDIES AND SOCIAL SCIENCES. – 2022.- P. 9-12.
27. Jalilova, A. S. (2022). Approaches to Etiotropic Therapy of Covid-19 in Outpatient Patients. INTERNATIONAL JOURNAL OF HEALTH SYSTEMS AND MEDICAL SCIENCES, 1(1), 41-44.
28. Mukhtarova Sh.A. (2022) Age-related features of clinical manifestations of giardiasis // International journal of medical sciences and clinical research 2022;17-21.
29. Jalilova A.S. (2022). FEATURES OF CLINICAL MANIFESTATIONS OF CYTOMEGALOVIRUS INFECTION IN CHILDREN. International Journal of Medical Sciences And Clinical Research, 2(09), 12–16. https://doi.org/10.37547/ijmscr/Volume02Issue09-04
30. Raximovich, O. A., Sadilloyevna, J. A., Abdulloyevna, M. S., & Farxodovich , R. F. (2022). Microbiological Indicators of Patients with Confirmed Sars-Cov-2 - Infection. Central Asian Journal of Medical and Natural Science, 3(2), 289-294. https://doi.org/10.17605/OSF.IO/9CFP6
31. Жалилова А. С. Дилноза Саётовна Косимова. Клинико–Лабораторная Характеристика Пациентов С Covid-19 И Предиктор Антибактериальной Терапии //CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES. – 2021. – С. 81-86.
32. Abdulloyevna, M. S. . (2023). Tez-Tez Kasal Bo’lgan Bolalarda O’tkir Respirator Kasalliklarning Klinik-Laboratoriya Xususiyatlari. AMALIY VA TIBBIYOT FANLARI ILMIY JURNALI, 2(12), 29–34. Retrieved from https://sciencebox.uz/index.php/amaltibbiyot/article/view/8680
33. Muxtorova, S. A. (2022). Clinical and laboratoriya features of acute respiratory disease in frequently ill children. Web of scientist: International scientific research journal, 1026-1030.
34. Mukhtarova, S. H. (2022). A.(2022) AGE-RELATED FEATURES OF CLINICAL MANIFESTATIONS OF GIARDIASIS. INTERNATIONAL JOURNAL OF MEDICAL SCIENCES AND CLINICAL RESEARCH, 17-21.
35. Mukhtorova Shokhida Abdulloevna. (2023). Microbiological Indicators of Patients Infected with SarsCov-2. Texas Journal of Medical Science, 21, 41–45. Retrieved from https://www.zienjournals.com/index.php/tjms/article/view/4116
36. Mukhtorova Shokhida Abdulloevna. (2023). CYTOMEGALOVIRUS INFECTIONS IN CHILDREN WITH PRIMARY AND SECONDARY IMMUNE DEFICIENCIES. Academia Science Repository, 4(06), 23–28. Retrieved from http://academiascience.com/index.php/repo/article/view/832
37. Aslonova.M.R. (2023). VITAMIN DEFICIENCY CASES RESULTING FROM PARASITIC DISEASES // Galaxy International Interdisciplinary Research Journal.-2023.-P. 404-409
38. Mukhtorova Shokhida Abdulloevna. (2023). CHARACTERISTIC FEATURES OF THE COURSE OF CITOMEGALOVIRUS INFECTION IN CHILDREN. Galaxy International Interdisciplinary Research Journal, 11(4), 484–487. Retrieved from https://giirj.com/index.php/giirj/article/view/5150.
39. Raximovich, O. A., Sadilloyevna, J. A., Abdulloyevna, M. S., & Farxodovich , R. F. (2022). Microbiological Indicators of Patients with Confirmed Sars-Cov-2 - Infection. Central Asian Journal of Medical and Natural Science, 3(2), 289-294. https://doi.org/10.17605/OSF.IO/9CFP6
40. Ш. А, М. (2023). Профилактика Сезонного Распространения Орви Среди Детей Раннего Возраста. AMALIY VA TIBBIYOT FANLARI ILMIY JURNALI, 2(12), 22–28. Retrieved from https://www.sciencebox.uz/index.php/amaltibbiyot/article/view/8678
41. M. I., M. . (2024). Features of the Clinical Course of Virus-Associated Glomerulonephritis in Children and Adolescents. Research Journal of Trauma and Disability Studies, 3(10), 163–169. Retrieved from https://journals.academiczone.net/index.php/rjtds/article/view/3676
42. Mukhammadieva M. I. (2024). PREVENTION OF COMPLICATIONS WITH SPONTANEOUS BACTERIAL PERITONITIS WITH LIVER CIRRHOSIS OF VIRAL ETIOLOGY. Web of Medicine: Journal of Medicine, Practice and Nursing, 2(12), 191–197. Retrieved from http://webofjournals.com/index.php/5/article/view/2595
