BIOCHEMICAL BASES OF THERAPY IN VETERINARY MEDICINE
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Keywords: Personalized Medicine, Drug Composition, Nutritional Biochemistry, Mechanism of ActionAbstrak
Abstract. The biochemical bases of therapy in veterinary medicine are critical for understanding how to effectively diagnose, treat, and manage diseases in animals. Here are some key aspects of how biochemistry informs therapeutic approaches: Pharmacokinetics examines how drugs are absorbed, distributed, metabolized, and excreted in the body. This knowledge helps veterinarians determine appropriate dosing regimens and routes of administration. Pharmacodynamics involves how drugs exert their effects on the body, including mechanisms of action, therapeutic effects, and potential side effects. Biochemical analyses reveal critical information about an animal's health status, allowing for the identification of disease processes and assessment of treatment responses through various biomarkers. These can include enzyme levels, electrolyte imbalances, and metabolic byproducts. Drug Composition and Mechanism of Action: Understanding the biochemical composition of therapeutic agents—including active ingredients and their mechanisms—enables veterinarians to select appropriate treatments for specific conditions. For instance, anti-inflammatory medications and antibiotics work by targeting specific biochemical pathways or infectious agents. Nutritional Biochemistry: Nutrition plays a vital role in therapy, as specific nutrients can influence healing and overall health. For example, employing specialized diets or supplements that contain antioxidants can support liver function or immune response during treatment. Personalized Medicine: Recognizing individual variability in animal patients, such as age, breed, genetic predispositions, and underlying health conditions, allows veterinarians to tailor treatments more effectively. Biochemical profiles can guide adjustments in therapy based on a patient's unique needs. Routine biochemical testing during therapy helps monitor the effects of medications on organ function and systemic health, allowing for swift adjustments and minimizing adverse effects. This is especially crucial in long-term or complex treatments. Understanding biochemical interactions between different drugs, as well as between drugs and food, helps to anticipate and manage potential side effects and interactions, ensuring safer treatment protocols
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1. Stockham S. L., Scott M. A. (ed.). Fundamentals of veterinary clinical pathology. – John Wiley & Sons, 2024.
2. Janas K. E. A., Tobias K. M., Aisa J. Clinical outcomes for 20 cats with congenital extrahepatic portosystemic shunts treated with ameroid constrictor ring attenuation (2002–2020) //Veterinary Surgery. – 2024. – Т. 53. – №. 2. – С. 243-253.
3. Reeves A. M. et al. HEMATOLOGY AND BIOCHEMICAL REFERENCE INTERVALS FOR FREE-RANGING PRONGHORN (ANTILOCAPRA AMERICANA) IN WEST TEXAS //Journal of Zoo and Wildlife Medicine. – 2024. – Т. 55. – №. 3. – С. 573-584.
4. Толегенов Н. С., Кереев А. К., Абдрахманов Р. Г. ГЕМАТОЛОГИЧЕСКИЕ И БИОХИМИЧЕСКИЕ ПОКАЗАТЕЛИ КРОВИ ПРИ ЦЕНУРОЗЕ //Вестник науки. – 2024. – Т. 4. – №. 10 (79). – С. 1202-1211.
5. Требухов А. В., Ракитин Г. А. Влияние пробиотика на биохимические показатели крови служебных собак //Вестник Алтайского государственного аграрного университета. – 2024. – №. 11 (241). – С. 47-52.
6. Тарасова Е. Ю., Матросова Л. Е. ИЗУЧЕНИЕ БИОХИМИЧЕСКИХ ПОКАЗАТЕЛЕЙ СЫВОРОТКИ КРОВИ КУР-НЕСУШЕК ПРИ СОЧЕТАННОМ МИКОТОКСИКОЗЕ НА ФОНЕ ПРИМЕНЕНИЯ МНОГОКОМПОНЕНТНОГО СРЕДСТВА «ГАЛЛУАСОРБ» 8 //Вестник КрасГАУ. – 2024. – №. 10. – С. 140-146.
7. Байкулов А. К., Убайдуллаева Г. Б., Хайитова Б. А. ЭНДОТЕЛИАЛЬНАЯ ДИСФУНКЦИЯ СОСУДОВ С ЭКСПЕРИМЕНТАЛЬНОЙ ГИПЕРЛИПОПРОТЕИНЕМИЙ //O'ZBEKISTONDA FANLARARO INNOVATSIYALAR VA ILMIY TADQIQOTLAR JURNALI. – 2023. – Т. 2. – №. 18. – С. 620-626.
8. Советов К. Т., Байкулов А. К. Динамика ИБС с корркекцией ЛДГ //Modern Scientific Research International Scientific Journal. – 2023. – Т. 1. – №. 9. – С. 47-55.
9. Байкулов А. К. и др. ТОКСИКОДИНАМИКА И ТОКСИКОКИНЕТИКА КОФЕИНА, СТРИХНИНА И РТУТИ //Yangi O'zbekiston taraqqiyotida tadqiqotlarni o'rni va rivojlanish omillari. – 2024. – Т. 12. – №. 1. – С. 92-100.
10. Байкулов А. К. и др. ВАЛИДАЦИЯ ПЕРЕГОНКИ ЛЕТУЧИХ ЯДОВ ВОДЯНЫМ ПАРОМ //Modern education and development. – 2024. – Т. 13. – №. 2. – С. 117-123.
11. Байкулов А. К. и др. ҚАНДЛИ ДИАБЕТА ҚАРШИ ДОРИ ВОСИТАЛАРИНИ ТОКСИКЛИГИ //Yangi O'zbekiston taraqqiyotida tadqiqotlarni o'rni va rivojlanish omillari. – 2024. – Т. 12. – №. 1. – С. 87-91.
12. Bayqulov A. K., Halimova S. A., Eshburieva N. R. Dynamics of the influence of lactate dehydrogenase during experimental myocardial infarction //World of Scientific news in Science. – 2024. – Т. 2. – №. 3. – С. 232-238.
13. Bayqulov A. K. et al. EXPERIMENTAL GIPERLIPOPROTEINEMIYANI XITOSAN HOSULALARI BILAN KORREKSIYASI //Zamonaviy fan va ta'lim yangiliklari xalqaro ilmiy jurnal. – 2024. – Т. 2. – №. 2. – С. 230-240.
14. Baykulov A. K., Halimova S. A., Murtazayeva N. K. Vascular endothelial dysfunctions with hyperlipoproteinemia //Golden brain. – 2023. – Т. 1. – №. 7. – С. 4-11.
15. Karjavov A., Fayzullaev N., Baykulov A. Production of acetone by catalytic hydration of acetylene //E3S Web of Conferences. – EDP Sciences, 2023. – Т. 389. – С. 01046.
16. Baykulov A. K., Hurramova S. G., Ubaydullayeva G. B. STUDYING OXIDATIVE STRESS OF LIPIDS DURING EXPERIMENTAL MYOCARDIAL INFARCTION IN RATS //Bulletin news in New Science Society International Scientific Journal. – 2024. – Т. 1. – №. 5. – С. 181-191.
17. Байкулов А. К., Саветов К. Т., Халиков К. М. РЕПАРАТИВНАЯ РЕГЕНЕРАЦИЯ КОЖИ ПРИ ЭКСПЕРИМЕНТАЛЬНОМ ТЕРМИЧЕСКОМ ОЖОГЕ С ИСПОЛЬЗОВАНИЕМ ХИТОЗАНА //АКТУАЛЬНЫЕ ПРОБЛЕМЫ БИОМЕДИЦИНЫ-2020. – 2020. – С. 291-292.
18. Ашурбоев Ш. Д. и др. ДОРИ ВОСИТАЛАРИНИНГ ЯРОҚЛИЛИК МУДДАТИНИ АНИҚЛАШ //ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ. – 2024. – Т. 57. – №. 10. – С. 147-151.
19. Байкулов А. К., Убайдуллаева Г. Б., Хайитова Б. А. ЭНДОТЕЛИАЛЬНАЯ ДИСФУНКЦИЯ СОСУДОВ С ЭКСПЕРИМЕНТАЛЬНОЙ ГИПЕРЛИПОПРОТЕИНЕМИЙ //O'ZBEKISTONDA FANLARARO INNOVATSIYALAR VA ILMIY TADQIQOTLAR JURNALI. – 2023. – Т. 2. – №. 18. – С. 620-626.
20. Ermanov R. T., Qarshiev S. M., Baykulov A. K. CHANGES IN THE NITRERGIC SYSTEM DURING EXPERIMENTAL HYPERCHOLESTEROLEMIA //World of Scientific news in Science. – 2024. – Т. 2. – №. 4. – С. 326-339.
21. Kenjayevich B. A. Dynamics of the nitroergic system in experimental hypercholesterolemia //Int Res J Med Med Sci. – 2023. – Т. 11. – №. 3. – С. 30-34.
