ERITMALARNING FAZAVIY MUVOZANATINING FARMATSEVTIKAGA TUTGAN O’RNI
Keywords:
Kalit so’zlar: eritma, muvozanat, faza, farmatsevtika, dori moddalari, diagramma,kristallanish, muvozanat, amorf shakl, ko-kristal, antibiotic, insulin preparati, nanotexnologiya.Abstract
Farmatsevtik sanoatda dori vositalarining fizik-kimyoviy jarayonlarini boshqarish dori vositalarining samaradorligi, xavfsizligi va sifatini ta’minlash uchun muhimdir. Eritmalarning fazaviy muvozanati dori vositalarining ishlab chiqarilishi, tozalanishi va organizmda so‘rilish jarayonlarini tushunish uchun zarur. Ushbu maqola fazaviy muvozanatning farmatsevtik texnologiyalardagi ahamiyati va uning asosiy qo‘llanilish sohalarini batafsil yoritadi.
References
1. Aulton M.E. Pharmaceutics: The Science of Dosage Form Design. Churchill Livingstone, 2002.
2. Martin A. Physical Pharmacy: Physical Chemical Principles in the Pharmaceutical Sciences. Lippincott Williams & Wilkins, 2011.
3. Brittain H.G. Polymorphism in Pharmaceutical Solids. CRC Press, 2016.
4. Yu L. Amorphous Pharmaceutical Solids: Preparation, Characterization and Stabilization. Advanced Drug Delivery Reviews, 2001.
5. Atkinson D. Pharmaceutical Crystal Engineering. Journal of Pharmacy and Pharmacology, 2019.
6. Singh A. et al. Role of Phase Equilibria in the Development of Pharmaceutical Systems. International Journal of Pharmaceutics, 2020.
7. Hancock B.C., Parks M. What is the True Solubility Advantage for Amorphous Pharmaceuticals? Pharmaceutical Research, 2000.
