PROBIOTIKLARNING IMMUNOMODULYATSION TA'SIRI: BOLALARDA O'TKIR RESPIRATORLI INFEKSIYALARNING OLDINI OLISH IMKONIYATLARI
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Kalit so'zlar :Probiotik, profilaktika, Lactobacillus plantarum, bolalar, mikrobiot, immunitet.##article.abstract##
Annotatsiya: Hozirgi kunda o'tkir respirator infektsiyalar (O`RI) bolalik davridagi muhim patologiya hisoblanadi (ular o'tkir respirator infektsiyalarning 90 foizini tashkil qiladi). Probiotiklarning turli xil kasalliklarda samaradorligi isbotlangan, ammo probiotiklarni profilaktika vositasi va organizmning infeksiyaga qarshi qarshiligini oshirish usuli sifatida ishlatish imkoniyatlari tobora muhim ahamiyat kasb etmoqda. Bolalar bilan o'tkazilgan ko'plab klinik tadqiqotlar shuni ko'rsatdiki, probiotiklar O`RI bilan kasallanganlar sonining kamayishiga, O`RI epizodining o'rtacha davomiyligining pasayishiga va antibiotiklardan foydalanish chastotasining pasayishiga, shuningdek, shamollash bilan bog'liq maktabgacha / maktabdagi darslarning bolalar tomonidan qoldirilishining kamayishiga yordam berdi. Probiotikdagi mikroblar shtammlarini inson tanasi uchun xavfsizligini va yaxshi tolerantligini hisobga olgan holda ehtiyotkorlik bilan tanlash, probiotiklarning ko'p yo'nalishli va fiziologik ta'siri klinik samaradorligi isbotlangan bir qator probiotiklarning paydo bo'lishiga yordam berdi. Ushbu maqolada Lactobacillus plantarum Sest 7315/7316 ning klinik amaliyotda samaradorligini tasdiqlovchi asosiy ma'lumotlar keltirilgan.
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