THE ROLE OF BIOLOGICAL FLUIDS IN THE DEVELOPMENT OF KIDNEY STONE DISEASE
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Keywords: Kidney, Biological fluids, Urine pH, Urinary Inhibitors of Crystal Formation, Blood Composition:##article.abstract##
Abstract: The role of biological fluids, particularly urine, in the development of
kidney stone disease is paramount to understanding its pathogenesis. This review
delves into the dynamics of biological fluids, including their composition,
physicochemical properties, and the balance of promoters and inhibitors of
crystallization. It explores recent insights into the influence of urine pH,
supersaturation levels, the impact of other bodily fluids, and emerging evidence on
extracellular vesicles and the microbiome. The findings underscore the importance of
modifying urinary composition through dietary and therapeutic measures to mitigate
stone formation risk.
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