TEZLASHTIRILGAN ESKIRTIRISH USULIDA YAROQLILIK MUDATINI ANIQLASH.

##article.authors##

  • Hilola Musayeva Usmonkul qizi ##default.groups.name.author##

##semicolon##

Kalit so'zlar: Dori vositalari, yaroqlilik muddati, tezlashtirilgan eskirtirish, kimyoviy barqarorlik, fizikaviy barqarorlik, dori sifatini tekshirish.

##article.abstract##

Annotatsiya:  Ushbu  maqolada  dori  vositalarining  yaroqlilik  muddatini 
tezlashtirilgan eskirtirish usuli yordamida aniqlash jarayoni tahlil qilingan. Tadqiqot 
dori  vositalarining  uzoq  muddatli  saqlash  sharoitlarida  o'zgarishi,  shu  jumladan 
ularning kimyoviy, fizikaviy va biologik barqarorligini baholashda foydalaniladigan 
zamonaviy  metodlar  va  usullarni  o'rganadi.  Tezlashtirilgan  eskirtirish 
texnologiyalarining samaradorligi va ularning dori vositalarining sifatini saqlashdagi 
o'rni alohida ta'kidlanadi. Tadqiqot natijalari dori sanoatida  mahsulotning  yaroqlilik 
muddatini  aniqlashda  tezlashtirilgan  testlardan  foydalanishning  muhimligini 
ko'rsatadi. 

##submission.citations##

Adabiyotlar.

1. Salvador J. A., Figueiredo S. A., Pinto R. M., Silvestre S. M. Bismuth compounds

in medicinal chemistry // Future Med Chem. 2012. Vol. 4, № 11. P. 1495–1523.

2. Pelgrift R. Y., Friedman A. J. Nanotechnology as a therapeutic tool to combat

microbial resistance // Adv Drug Deliv Rev. 2013. Vol. 65, № 13–14. P. 1803–

1815.

3. Hernandez-Delgadillo R., Velasco-Arias D., Diaz D. et al. Zerovalent bismuth

nanoparticles inhibit Streptococcus mutans growth and formation of biofilm // Int J

Nanomedicine. 2012. Vol. 7. P. 2109– 2113.

4. Hernandez-Delgadillo R., Velasco-Arias D., Martinez-Sanmiguel J. J. et al.

Bismuth oxide aqueous colloidal nanoparticles inhibit Candida albicans growth and

biofilm formation // Int J Nanomedicine. 2013. Vol. 8. P. 1645– 1652

5. Salvador J. A., Figueiredo S. A., Pinto R. M., Silvestre S. M. Bismuth compounds

in medicinal chemistry // Future Med Chem. 2012. Vol. 4, № 11. P. 1495–1523.

6. Ge R. G., Sun H. Z. Bioinorganic chemistry of bismuth and antimony: target sites

of metallodrugs // Acc Chem Res. 2007. Vol. 40, № 4. P. 267–274.

7. Ge R. G., Sun X, Gu Q. et al. A proteomic approach for the identification of

bismuth-binding proteins in Helicobacter pylori // J Biol Inorg Chem. 2007. Vol.

12, № 6. P. 831–842.

##submission.downloads##

##submissions.published##

2024-11-23